I have a NAA Mini Revolver in .22 Mag. I figured on carrying it while jogging and loading the first chamber or two with shotshells. I jog up and down the road in front of where I live (out in the sticks) and there are plenty of snakes around. Well, I thought I would try the shotshells out on a water filled bottle. To say it was unimpressive would be the understatement of the year! Heck, the shot barely penetrated the bottle. Now, the NAA sure aint the most accurate gun I ever owned, as it will shoot dang near a foot low with regular .22 Mags. But, the shotshells actually hit the bottle pretty good, it just barely penetrated it. I reckon it might kill a snake, but I really don't want to find out! I have used the regular .22 LR many times and they seem to penetrate better. Of course, that was out of a 6 1/2 barreled Single Six vs. the barely over an inch NAA Mini Revolver.